Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
This recombinant monoclonal mouse anti-6X His tag with CF and reg 790 dye CF and reg dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness photostability and conjugate specificity CF and reg 790 dye has excitation/emission at 783/808 nm
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
PROTAC B-Raf degrader 1 (compound 2) is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf based on Cereblon ligand with anti-cancer activity.
Can accelerate the degradation of B-Raf by recruiting ubiquitin-proteasome system.
Affects the expression of Mcl-1, a downstream protein of B-Raf.
Induces apoptosis in MCF-7 cells, with an apoptosis rate of 76.70% (64.00% early apoptosis, 12.70% late apoptosis) after 24 h incubation at 20 μM.
Arrests cell cycle at the G2/M phase.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor that exhibits antitumor activity. It demonstrates a KD of 5.0 μM-15 μM for cyclophilin A (CYPA) binding affinity. This compound is intended for research use only.
Potent RAS and RAS-RAF inhibitor
Exhibits antitumor activity
Has a KD of 5.0 μM-15 μM for cyclophilin A (CYPA) binding affinity
Shows EC50 of 0.5 μM-5.0 μM for BRAF-GTP-KRAS-G12C disruption in H358 cells
Demonstrates IC50 of 1.0 μM-10 μM for pERK inhibition in H358 cells
For research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More